Drug Combination Promising as Pre-Sex Birth Control
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A drug combination that uses emergency contraception and a cyclo-oxygenase-2 (COX-2) inhibitor may effectively disrupt ovulation, making it the first potential candidate for on-demand,
pericoital oral contraception, according to an exploratory pilot study.
Among a group of nine patients, six demonstrated ovulation disruption after taking a combination drug of ulipristal acetate (UA) and meloxicam, reported Erica Cahill, MD, of Stanford
University in California, and colleagues.
In total, eight of the participants experienced incomplete ovulation, or some signs of ovulatory dysfunction, they wrote in BMJ Sexual & Reproductive Health.
Menstrual cycle length was approximately 3 days longer in the treatment cycle than in the baseline cycle (31.9 days vs 28.6 days, P