Enzymatic behaviour of the product of coenzyme a-norepinephrine reaction


Enzymatic behaviour of the product of coenzyme a-norepinephrine reaction

Play all audios:


ABSTRACT REACTION of the sulphydryl group of coenzyme A _in vitro_ with oxidation products of epinephrine and nor-epinephrine has been demonstrated by chemical measurement of the residual


—SH groups1. The coenzyme A–catecholamine compounds may well represent an important stage in intermediary metabolism, since their breakdown may lead to regeneration of coenzyme A and


formation of physiologically active catecholamine derivatives. Furthermore, if coenzyme A is inactivated by these reactions, an explanation may be at hand for some of the physiological


effects of the catechol amines. The work reported here evaluates the reactivity and stability of the coenzyme A–catecholamine derivatives in the light of their enzymatic activity _in vitro_.


Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this


journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now


Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer


support SIMILAR CONTENT BEING VIEWED BY OTHERS AN ESSENTIAL ROLE OF ACETYL COENZYME A IN THE CATALYTIC CYCLE OF INSECT ARYLALKYLAMINE N-ACETYLTRANSFERASE Article Open access 14 August 2020


CHANOCLAVINE SYNTHASE OPERATES BY AN NADPH-INDEPENDENT SUPEROXIDE MECHANISM Article Open access 05 March 2025 BIOCOORDINATION REACTIONS IN COPPER(II) IONS AND PHOSPHOCHOLINE SYSTEMS


INCLUDING PYRIMIDINE NUCLEOSIDES AND NUCLEOTIDES Article Open access 04 July 2023 REFERENCES * Roston, S., _J. Biol. Chem._, 235, 3315 (1960). CAS  PubMed  Google Scholar  * Ellman, G. L.,


_Arch. Biochem. Biophys._, 74, 443 (1958). Article  CAS  Google Scholar  * Novelli, G. D., _Meth. Biochem. Anal._, 2, 189 (1955). CAS  Google Scholar  Download references AUTHOR INFORMATION


AUTHORS AND AFFILIATIONS * University of Louisville, School of Medicine, Kentucky SIDNEY ROSTON Authors * SIDNEY ROSTON View author publications You can also search for this author inPubMed 


Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE ROSTON, S. Enzymatic Behaviour of the Product of Coenzyme A-Norepinephrine Reaction.


_Nature_ 197, 75–76 (1963). https://doi.org/10.1038/197075a0 Download citation * Issue Date: 05 January 1963 * DOI: https://doi.org/10.1038/197075a0 SHARE THIS ARTICLE Anyone you share the


following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer


Nature SharedIt content-sharing initiative