Selected physical activities and the risk of endometrial cancer
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ABSTRACT The relationship between various indicators of physical activity and endometrial cancer risk was analysed using data of a case-control study conducted in 1988-1991 in Switzerland
and Italy on 274 histologically confirmed cases and 572 controls admitted to hospital for acute, non neoplastic, non hormone-related diseases. Using a self-rated assessment of total physical
activity, there was a systematic tendency for the cases to report more frequently 'low' or 'very low' physical activity. The relative risks were similar for 'very
high' or 'moderately high' physical activity, but increased in the two lowest levels, with point estimates, in various decades of age, between 1.3 and 2.3 for 'moderately
low' and over 2.5 for 'very low' physical activity. Although the association was apparently stronger at older ages, all the trends in risk were significant. Allowance for
major identified potential distorting factors, including body mass index and a measure of total energy intake, could explain only in part the association, and the inverse trends in risk
remained statistically significant. When selected types of physical activity were analysed, no association was observed with climbing stairs or walking, but the risk estimates for the lowest
level of activity was over 4 for housework, and between 1.5 and 1.9 for sport and leisure and occupational activity. Thus, the present findings suggest that a moderate or high physical
activity is an indicator of reduced endometrial cancer risk, although this observation still requires epidemiologic confirmation and clearer definition from a pathogenic point of view.
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Vaudois des Tumeurs, CHUV, Lausanne, Switzerland F Levi Authors * F Levi View author publications You can also search for this author inPubMed Google Scholar * C La Vecchia View author
publications You can also search for this author inPubMed Google Scholar * E Negri View author publications You can also search for this author inPubMed Google Scholar * S Franceschi View
author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Levi, F., La Vecchia, C.,
Negri, E. _et al._ Selected physical activities and the risk of endometrial cancer. _Br J Cancer_ 67, 846–851 (1993). https://doi.org/10.1038/bjc.1993.155 Download citation * Issue Date: 01
April 1993 * DOI: https://doi.org/10.1038/bjc.1993.155 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable
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