Early-onset glaucoma in Axenfeld–Rieger anomaly: long-term surgical results and visual outcome


Early-onset glaucoma in Axenfeld–Rieger anomaly: long-term surgical results and visual outcome

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To determine the long-term surgical and visual outcomes in Indian children with early-onset glaucoma associated with Axenfeld–Rieger anomaly (ARA).


This is a retrospective analysis of 44 eyes of 24 consecutive children with early-onset glaucoma (within 3 years of age) and ARA who underwent glaucoma surgery over a 20-year period


(1991–2010) by a single surgeon. Main outcome measures were pre- and postoperative intraocular pressures (IOPs), corneal clarity, visual acuities (VAs), refractive errors, success rate, time


of surgical failure, and complications.


The series consisted of 38 primary combined trabeculotomy–trabeculectomy (CTT) and 6 primary trabeculectomy procedures (Schlemm’s canal could not be identified in these eyes). There was a


statistically significant reduction in IOP postoperatively (27.07±4.88 vs 14.88±3.62 mm Hg; P