Variable suppression of TSH by human chorionic gonadotropin during early pregnancy


Variable suppression of TSH by human chorionic gonadotropin during early pregnancy

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Haddow JE et al. (2008) Variability in thyroid stimulating hormone suppression by human chorionic gonadotropin during early pregnancy. J Clin Endocrinol Metab 93: 3341–3347


An inverse relationship has been described between maternal serum TSH and human chorionic gonadotropin (hCG) levels during early pregnancy. TSH levels reach a nadir at around 10 weeks'


gestation, at which time hCG levels peak. In addition, free T4 levels might be elevated, although other features of hyperthyroidism are usually absent.


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