Sick of the flu | Nature Reviews Immunology


Sick of the flu | Nature Reviews Immunology

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Access through your institution Buy or subscribe In mice infected intranasally with the A/Puerto Rico/8/34 (PR8) influenza virus strain, both the lung and small intestine, but not nonmucosal


liver and kidney tissue, showed signs of severe injury. Influenza virus could not be detected in the small intestine of intranasally infected mice, and mice infected intragastrically with


PR8 did not have injury to the small intestine; therefore, influenza virus does not directly cause injury to the intestinal mucosa. > influenza virus infection mediates intestinal injury 


by altering the > composition of the intestinal microbiota This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe


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customer support REFERENCES * Wang, J. et al. Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammation. _J. Exp. Med._


http://dx.doi.org/10.1084/jem.20140625 (2014) Download references Authors * Kirsty Minton View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND


PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Minton, K. Sick of the flu. _Nat Rev Immunol_ 14, 781 (2014). https://doi.org/10.1038/nri3773 Download citation *


Published: 14 November 2014 * Issue Date: December 2014 * DOI: https://doi.org/10.1038/nri3773 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content:


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