Experimental evidence for a pathogenic role of anti-pla2r1 antibodies in membranous nephropathy
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Access through your institution Buy or subscribe Circulating anti-phospholipase A2 receptor 1 (anti-PLA2R1) antibodies are found in 70–80% of patients with membranous nephropathy. A new
study provides experimental evidence of the pathogenicity of these antibodies in this disease. The researchers conclude that human anti-PLA2R1 antibodies have a pathogenic role in membranous
nephropathy. However, they comment that their data do not exclude the possibility that other factors in the plasma of patients may also contribute to the development of the disease. This is
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ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES ORIGINAL ARTICLE * Reinhard, L. et al. Pathogenicity of human
anti-PLA2R1 antibodies in minipigs: a pilot study. _J. Am. Soc. Nephrol._ https://doi.org/10.1681/ASN.0000000000000068 (2023) Article PubMed Google Scholar Download references AUTHOR
INFORMATION AUTHORS AND AFFILIATIONS * Nature Reviews Nephrology http://www.nature.com/nrneph Ellen F. Carney Authors * Ellen F. Carney View author publications You can also search for this
author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Ellen F. Carney. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Carney, E.F.
Experimental evidence for a pathogenic role of anti-PLA2R1 antibodies in membranous nephropathy. _Nat Rev Nephrol_ 19, 213 (2023). https://doi.org/10.1038/s41581-023-00697-x Download
citation * Published: 27 February 2023 * Issue Date: April 2023 * DOI: https://doi.org/10.1038/s41581-023-00697-x SHARE THIS ARTICLE Anyone you share the following link with will be able to
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