Retraction note: the hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase


Retraction note: the hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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Retraction of: _Nature_ https://doi.org/10.1038/nature14492 Published online 27 May 2015 The Editors have retracted this paper because, in their view, data in Extended Data Fig. 1d and


Extended Data Fig. 4a are unreliable. Issues with the original antibody used in Extended Data Fig. 1d and 4a have been identified. The western blots showing an increase in secreted LOX in


bone-trophic and hypoxic MDA-MB-231 cells, and shRNA knockdown of LOX in 4T1 cells, present unreliable bands. R.L. agrees with the retraction. All other authors disagree with the retraction


and believe the findings are still valid. AUTHOR INFORMATION Author notes * These authors contributed equally: Alison Gartland & Janine T. Erler AUTHORS AND AFFILIATIONS * Biotech


Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark Thomas R. Cox, Lara Perryman, Anette M. Høye, Rune Linding & Janine T. Erler * Hypoxia and


Metastasis Team, Cancer ResearchUKTumour Cell Signalling Unit, The Institute of Cancer Research, London, UK Thomas R. Cox, Demelza Bird, Georgina Lang & Janine T. Erler * The Mellanby


Centre for Bone Research, The University of Sheffield, Sheffield, UK Robin M. H. Rumney, Ankita Agrawal, Norain Ab Latif, Hamish Forrest, Holly R. Evans, Iain D. Huggins & Alison


Gartland * Cellular Signal Integration Group (C-SIG), Technical University of Denmark (DTU), Lyngby, Denmark Erwin M. Schoof & Rune Linding Authors * Thomas R. Cox View author


publications You can also search for this author inPubMed Google Scholar * Robin M. H. Rumney View author publications You can also search for this author inPubMed Google Scholar * Erwin M.


Schoof View author publications You can also search for this author inPubMed Google Scholar * Lara Perryman View author publications You can also search for this author inPubMed Google


Scholar * Anette M. Høye View author publications You can also search for this author inPubMed Google Scholar * Ankita Agrawal View author publications You can also search for this author


inPubMed Google Scholar * Demelza Bird View author publications You can also search for this author inPubMed Google Scholar * Norain Ab Latif View author publications You can also search for


this author inPubMed Google Scholar * Hamish Forrest View author publications You can also search for this author inPubMed Google Scholar * Holly R. Evans View author publications You can


also search for this author inPubMed Google Scholar * Iain D. Huggins View author publications You can also search for this author inPubMed Google Scholar * Georgina Lang View author


publications You can also search for this author inPubMed Google Scholar * Rune Linding View author publications You can also search for this author inPubMed Google Scholar * Alison Gartland


View author publications You can also search for this author inPubMed Google Scholar * Janine T. Erler View author publications You can also search for this author inPubMed Google Scholar


CORRESPONDING AUTHORS Correspondence to Alison Gartland or Janine T. Erler. ABOUT THIS ARTICLE CITE THIS ARTICLE Cox, T.R., Rumney, R.M.H., Schoof, E.M. _et al._ Retraction Note: The hypoxic


cancer secretome induces pre-metastatic bone lesions through lysyl oxidase. _Nature_ 617, 208 (2023). https://doi.org/10.1038/s41586-023-06048-x Download citation * Published: 17 April 2023


* Issue Date: 04 May 2023 * DOI: https://doi.org/10.1038/s41586-023-06048-x SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link


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